05.31.07

Affinity Seeks Epigenomics Scientist in San Diego, CA

Posted in careers at 12:18 pm by Trevor

Affinity Scientific, a scientific staffing and recruitment firm, is seeking qualified candidates for a scientist in research and development with epigenomics experience.

The following is a reprint of the position information as supplied by Affinity Scientific.

Scientist - Epigenomics

POSITION PURPOSE:

The position requires responsibility for planning and executing research and development projects and collaborations in the Molecular Applications department. Candidates will be applying biochemical and molecular biological methods for the development of novel methods for genotyping, loss-of-heterozygocity (LOH) analysis and elucidation of epigenetic changes, in particular cytosine methylation, and other applications in the field of cancer research. A prerequisite for the position is a profound scientific background in molecular biology, biochemistry, design of experiments (DOE). Experience in statistical data analysis and data analysis tools like Excel and MatLab or R is preferred. Expertise in mass spectrometry and a medical background with a focus in cancer research are highly advantageous.

ESSENTIAL DUTIES AND RESPONSIBILITIES:

Responsible for planning, implementing and executing research and development projects within the Molecular Applications Department
Serves as a Molecular Biology and Cancer Research subject matter expert that is a resource within the company
Develops next versions of the company’s methods for analysis of epigenetic changes as well as inception and development of novel genotyping and comparative sequence analysis applications including methods such as ultrasensitive detection of methylation and detection of mutations in circulating tumor DNA.
Works on problems of diverse scope where experimental setup requires DOEs (Design of Experiment) and where analysis of data requires computational capabilities in Excel and MatLab or R.
Is able to select appropriate model systems and clinical samples for proof-of-concept of the developed methods
Strives to achieve objectives as set forth by supervisor and/or project lead
Executes laboratory research, and is responsible for ensuring projects and tasks are completed within the established time frame
Determines & develops approach to solutions exercising judgment within generally defined practices and policies in selecting methods and techniques for obtaining solutions. Works under limited direction
Expected to maintain a broad knowledge of and high degree of competence in the field by staying abreast of state-of-the-art principles and theories along with high technical visibility throughout the functional area
Responsible for programming and usage of liquid handling equipment
Tunes and calibrates laboratory instruments
Assists in projects requiring collaborations with other research development personnel within the Molecular Applications Department, inter-departmental Projects, as well as collaborations with external partners.

MINIMUM EDUCATION & PREVIOUS EXPERIENCE REQUIRED:

MD and/or PhD in Molecular Biology/Biochemistry, or closely related field, with 2-5 years experience in a research and/or development environment. Postdoctoral may serve as experience.
Experience in statistical data analysis and data analysis tools.

KNOWLEDGE, SKILLS & ABILITIES:

Requires hands-on experience with advanced molecular biology and biochemistry of nucleic acids and DNA preparation from various sample sources.
Hands-on experience with high-throughput genotyping and sequencing technologies is a plus
Proven track record in molecular biology research, cancer research and product and/or technology development
Expertise in DOE and statistical data analysis tools like Excel, MatLab or R
Consistently meeting critical deadlines
Ability to work in a team environment
Demonstrated technical proficiency, effective problem solving and critical thinking skills required
Proficient computer literacy in Microsoft Office
Excellent communication, interpersonal and organizational skills

To apply please send electronic copy of CV to mwells@affinityscientific.com.

Margaux Wells
Affinity Scientific, LLC
4660 La Jolla Village Drive
Suite 500
San Diego, CA 92122
(858) 535-4874
www.affinityscientific.com