histones

Epigenomic Modifications Predict Active Promoters and Gene Structure in Toxoplasma gondii

Friday, June 8th, 2007

A new research article appeared today in the open access journal PLoS Pathogens with new insights into the epigenetics modifications regulating gene expression in the human pathogen Toxoplasma gondii:
Apicomplexan parasites, including Toxoplasma gondii, are responsible for a variety of deadly infections, but little is understood about how these important pathogens regulate gene expression. Initial studies [...]

Epigenetics Researcher C. David Allis Grabs Gairdner Award

Thursday, April 19th, 2007

C. David Allis of The Rockefeller University is one of five scientists to receive a 2007 Gairdner International Award. Allis is recognized for his work on how histones affect genome stability and gene transcription. Each award winner receives US$30,000 and a statue at an award dinner to be held on October 25 in Toronto, Canada.
The [...]

Histone Modifications Regulate Pluripotency in the Early Mouse Embryo

Tuesday, February 6th, 2007

Earlier this year, a group affiliated with Cambridge University at the Wellcome Trust/Cancer Research UK Gordon Institute reported in Nature that epigenetics, specifically methylation of certain arginine residues of histone H3, directly contribute to cell fate and success in the four-cell stage embryo in the mouse model. These findings confront the widely accepted paradigm that [...]