03.20.06

Epigenetics implicated in clinical anti cancer resistance

Posted in cancer, research articles at 10:17 pm by Shane

A research team with the Centre of Oncology and Applied Pharmacology at Glasgow University postulate an epigenetic mechanism in driving polygenic resistance in cancer patients. The UK group suggests that the current focus of “specific genes or biochemical pathways” for acquired resistance to anti cancer drugs is an “oversimplification.” Rather, aberrant methylation of multiple genes occuring simultaneously during tumor development may be the key to cancer resistance. www.nature.com